Treatment failure in tuberculosis

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Treatment failure in tuberculosis.

Treatment of latent tuberculosis (TB) infection with 3 months of rifampicin/isoniazid is a major part of preventive TB programmes. The effectiveness of treatment of latent TB infection can only be assessed by rates of subsequent breakdown and there are few outcome data for this combination of rifampicin/isoniazid. Therefore, the aim of the present study was to estimate the failure rate followin...

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Treatment failure of tuberculosis due to concomitant pathology.

Introduction Tuberculosis is a worldwide problem. Nearly 3 million cases of tuberculosis occur per year in Southeast Asia alone.1 Several factors contribute to treatment failure and significant morbidity and mortality. While the most common causes in the "Third World" include poor compliance, late presentation, improper therapy, and the development of drug resistance2, underdiagnosis of this di...

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Microbiota have recently been shown to be associated with many disease conditions. However, the microbiota associated with tuberculosis (TB) infection, recurrence and treatment outcome have not been systematically characterized. Here, we used high throughput 16S RNA sequencing to analyze the sputum microbiota associated with Mycobacterium tuberculosis infection and also to identify the microorg...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2007

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.00092406